“Results are similar for confirmed and suspected cases, both in terms of clinical and epidemiological findings. Pseudo-chilblain was seen more in younger patients and vesicular lesions more in middle-aged patients livedo or necrosis was associated with more severe cases of COVID-19 and seen in older patients. įindings showed that skin manifestations largely appeared “late in the evolution” of the disease and behind other symptoms, though in 15% of cases, vesicular lesions appeared “early in the course of the disease” and ahead of other symptoms. Patient demographics, symptom timing, severity and prognosisĪssociations with different patient demographics, timing in relation to symptoms, severity, and prognosis were also detailed and illustrations of these patterns provided “to allow for easy recognition”, the researcher said. Dermatologists also perceived an increased number of herpes zoster cases in COVID-19 patients,” the researchers wrote. “A few patients showed other manifestations such as enanthem or purpuris flexural lesions. Other vesicular eruptions like small monomorphic vesicles were identified in 9% of cases and livedo or necrosis in 6%. Urticarial lesions, mostly found on the trunk, and pseudo-chilblain, found on hands and feet, were each found in 19% of cases. Skin manifestations categorised as ‘other maculopapules’ were identified in 47% of cases, some with perifollicular distribution and varying degrees of scaling. The researchers used a nationwide collection survey of images and clinical data from 375 cases of confirmed and suspected COVID-19, provided by Spanish dermatologists between April 3 – April 16, 2020.įindings from the survey enabled the team to describe five major clinical cutaneous patterns of the COVID-19 disease: acral areas of erythema-oedema with some vesicles or pustules (pseudo-chilblain) other vesicular eruptions urticarial lesions other maculopapules and livedo or necrosis. This current study, they said, described a “large, representative sample of patients with unexplained skin manifestations and a diagnosis of COVID-19 using a consensus method to define morphological patterns associated with COVID-19”.įindings, they said, “may help clinicians approach patients with the disease and recognise paucisymptomatic cases”. Nationwide image and clinical data analysis “Previous descriptions of cutaneous manifestations of COVID-19 were case reports and mostly lacked illustrations,” the researchers wrote. Writing in the British Journal of Dermatology, a team of researchers from hospital universities across Spain – led from Madrid and Barcelona – described cutaneous manifestations of the novel coronavirus (COVID-19) disease which they said had, so far, been “poorly characterised”.
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